

Results of the December 2010 and January 2011 Alberta Cancer Grant Programs
Alberta Innovates – Health Solutions (AIHS) and the Alberta Cancer Foundation (ACF) are pleased to announce the results of the December 2010 Alberta Cancer Research Operating Grants, Alberta Cancer High Risk for High Return Grants and the January 2011 Alberta Cancer Bridge, Pilot and Limited Term Project Grants competitions.
The Alberta Cancer Grants Program provides opportunities for high-quality researchers who are actively involved in research that is directly related to the problem of cancer. Funds available in these competitions are to support either single or multiple investigators in one of the award categories below:
- Alberta Cancer Research Operating Grants
- Alberta Cancer High Risk for High Returns Grants
- Alberta Cancer Bridge, Pilot and Limited Term Project Grants
On behalf of their respective Boards, Dr. Jacques Magnan, AIHS CEO, and Darryl Diletzoy, ACF Acting CEO, congratulate the successful applicants and acknowledge and thank all applicants for their substantial efforts.
AIHS and ACF acknowledge and thank Alberta Health and Wellness for the Alberta Cancer Prevention Legacy Fund to help support this program.
Applications
A total of 106 letters of intent were received to the Operating Grant and High Risk for High Returns competitions which resulted in 90 full applications being received in December 2010. In January 2011, 38 applications were received for the Alberta Cancer Bridge, Pilot and Limited Term Project Grants.
These represent a higher than normal application pressure.
Assessments and Decisions
The Alberta Cancer Research Operating Grants and the Alberta Cancer High Risk for High Returns Grants applications were assessed by the Alberta Cancer Grant Advisory Committees during meetings held on April18 to 21, 2011. The Alberta Cancer Bridge, Pilot and Limited Term Project Grants applications were assessed by the Alberta Bridge Pilot & Limited Term Grant Advisory Committee during a meeting held on February 28, 2011.
AIHS and ACF wish to acknowledge the substantial assistance provided by the Advisory Committee members and external reviewers and their important ongoing contributions to the missions of AIHS and ACF.
Formal letters of offer will be sent to the Principal Investigators which include information regarding funding and the specific terms and conditions under which the awards are offered. The letter will also contain reviewer comments about the individual’s application. The list of successful applicants is provided for information only. The formal letters will serve as the AIHS and ACF official decision should there be any discrepancy with the material on the website.
Results
For the December 2010 competition, there were 10 successful applications (15%) for the Alberta Cancer Research Operating Grants competition and 9 successful applications (41%) for the Alberta Cancer High Risk for High Returns Grants competition.
For the January 2011 competition, there were 8 successful applications (21%) for the Alberta Cancer Bridge, Pilot and Limited Term Project Grants competition.
The names of the successful applications are provided below.
Alberta Cancer Research Operating Grants
Principal Investigator |
Department |
Faculty |
Institution |
Project Title |
| Beattie, Tara L. | Biochemistry & Molecular Biology | Medicine | University of Calgary | A Molecular Understanding of Telomerase in Genomic Stability, Cell Survival and Cancer |
| Bebb, Gwyn | Oncology | Medicine | University of Calgary | PARP-1 Inhibition in ATM Deficient Gastric and Lung Cancer |
| Ingham, Robert J. | Medical Microbiology & Immunology | Medicine & Dentistry | University of Alberta | The Function and Regulation of JunB in ALK+ ALCL |
| Joseph, Kurian J. | Oncology | Medicine & Dentistry | University of Alberta | Preventing or Reducing Acute and Late Effects of Radiation Therapy in Patients with Solid Tumors. Advanced Technology Meets Clinical Outcomes. |
| Kovalchuk, Olga | Biological Sciences | Arts & Science | University of Lethbridge | Epigenetic Mechanisms of Radiation and Chemotherapy-induced Germline Genome Instability |
| Leng, Roger | Laboratory Medicine & Pathology | Medicine & Dentistry | University of Alberta | Molecular Mechanism of Negative Regulation of Tumor Suppressor p53 |
| Nguyen, Minh Dang | Clinical Neurosciences | Medicine | University of Calgary | Of DNA Damage and DNA Repair: The Story of the Spindle Assembly Factor TPX2 |
| Schriemer, David C. | Biochemistry & Molecular Biology | Medicine | University of Calgary | Evaluating the Function and Therapeutic Potential of a Novel Microtubule Stabilizing Agent |
| Senger, Donna L. | Oncology | Medicine | University of Calgary | Characterization and Therapeutic Targeting of p75NTR in Glioma Tumourigenesis |
| Yong, Voon Wee | Clinical Neurosciences | Medicine | University of Calgary | Enhancing Monocytoid Cell Activity to Curb Brain Tumor Initiating Cells |
Alberta Cancer High Risk for High Returns Grants
Principal Investigator |
Department |
Faculty |
Institution |
Project Title |
| Evans, David H. | Medical Microbiology & Immunology | Medicine & Dentistry | University of Alberta | Tuning the Oncolytic Properties of Vaccinia Virus through Mutation of Proteins Catalyzing Nucleotide Biosynthesis |
| Fear, Elise C. | Electrical & Computer Engineering | Schulich School of Engineering | University of Calgary | Clinical Evaluation of a New Approach to Breast Imaging with Microwaves |
| Kubes, Paul | Physiology & Pharmacology | Medicine | University of Calgary | Visualizing and Killing Metastases in Liver |
| Riabowol, Karl T. | Biochemistry & Molecular Biology | Medicine | University of Calgary | The ING3 Epigenetic Chromatin Regulator in Prostate Cancer |
| Sawyer, Michael B. | Oncology | Medicine & Dentistry | University of Alberta | Mechanisms of Tyrosine Kinase Inhibitor Toxicity |
| Spratlin, Jennifer L. | Oncology | Medicine | University of Alberta | A Multicentre, Randomized, Open Label, Phase III Study of Gemcitabine Versus FOLFOX in the First Line Setting for Metastatic Pancreatic Cancer Patients Using Upfront Human Equilibrative Nucleoside Transporter 1 (hENT1) Biomarker Testing |
| Uludag, Hasan | Chemical & Materials Engineering | Engineering | University of Alberta | siRNA Based Molecular Therapy for Reversal of Drug Resistance in Leukemia |
| Weljie, Aalim M. | Biological Sciences | Science | University of Calgary | Lipidomics of Tumor Progression: Eicosanoids and Breast Cancer |
| Wuest, Frank R. | Oncology | Medicine & Dentistry | University of Alberta | In Vivo Chemistry for Pretargeted Molecular Imaging and Therapy of Cancer |
Alberta Cancer Bridge, Pilot and Limited Term Project Grants
Principal Investigator |
Department |
Faculty |
Institution |
Project Title |
| Fu, YangXin | Obstetrics & Gynaecology | Medicine & Dentistry | University of Alberta | Role of Notch in Ovarian Cancer Stem Cells |
| Gailer, Juergen | Chemistry | Science | University of Calgary | Binding Studies of Platinum-based Anticancer Drugs to Plasma Proteins to Gain New Insight into their Toxic Side-effects in Pediatric Cancer Patients |
| Ingham, Robert J. | Medical Microbiology & Immunology | Medicine & Dentistry | University of Alberta | Does the Granzyme B Serine Protease Contribute to the Invasiveness or Tumorigenicity of Anaplastic Large Cell Lymphoma-positive, Anaplastic Large Cell Lymphoma? |
| Kovalchuk, Olga | Biological Sciences | Arts & Science | University of Lethbridge | Uncovering Biological Effects of THz Radiation - A Pilot Study |
| Shaw, Andrew R. | Oncology | Medicine & Dentistry | University of Alberta | Bcl10: A Novel Role in DNA Repair |
| Spratlin, Jennifer L. | Oncology | Medicine & Dentistry | University of Alberta | Biomarker Directed Adjuvant Therapy for Resected Pancreas Cancer |
| Thomas, Bejoy C. | Oncology | Medicine | University of Calgary | Emergency Room Visits and Palliative Care Services: The Canary in the Coal Mine? |
| Underhill, (Darrell) Alan | Oncology | Medicine & Dentistry | University of Alberta | Regulation of PAX3 Structure and Activity in Melanoma |
