Alberta Innovates- Health Solutions

TABLE OF CONTENTS

EXECUTIVE SUMMARY

SECTION 1:

• INTRODUCTION AND TERMS OF REFERENCE OF THE STUDY
  • Background
  • Terms of Reference

SECTION 2:

• METHODS

SECTION 3:

• IS THE WORK ON METHODS FOR ASSESSMENT OF RESEARCH BENEFITS INTERNATIONALLY GENERALIZABLE OR IS AHFMR OR ITS CONTEXT DIFFERENT?
  • Introduction
  • Is the Alberta Health Care System So Different?
  • The local objectives for research
  • The Implications of the Alberta Context
  • The Range of AHFMR Funding

SECTION 4:

• APPLYING THE BUXTON/HANNEY MODEL TO AHFMR-FUNDED HSR RESULTS FROM THE CASE STUDIES
  • Introduction
  • Case-study 1: Diagnostic methods for obstructive sleep apnea (OSA)
  • Case-study 2: Insight into back x-rays
  • HTA Unit Products
  • Case-study 3(a): Stereotactic radiosurgery: options for Albertans
  • Case-study 3(b): Telephone nurse triage services
• CONCLUSIONS FROM HSR CASE STUDIES

SECTION 5:

• EXTENDING THE MODEL TOWARDS CLINICAL AND BASIC BIOMEDICAL RESEARCH
  • Introduction
  • Justifying basic science
  • Experience with the case studies
  • Case-study 4: Transplantation of pancreatic islets of Langerhans
  • Case-study 5: Ligament healing
  • Case-study 6: Electrophysiology of the heart
  • Case-study 7: Lipid metabolism
• CONCLUSIONS FROM THE CASE STUDIES

SECTION 6:

• THE NEXT STEPS
  • Immediate use by the AHFMR
• FURTHER DEVELOPMENTAL WORK BY THE AHFMR
• THE BROADER RESEARCH ISSUES
• REFERENCE LIST

This Report has been prepared on the basis of available information of which the Foundation is aware from public literature and expert opinion, and attempts to be current to the date of publication. It has been externally reviewed. Additional information and comments relative to the Report are welcome, and should be sent to:

President and Chief Executive Officer
Alberta Heritage Foundation for Medical Research
3125 ManuLife Place, 10180 - 101 Street
Edmonton
Alberta T5J 3S4
CANADA

Tel: 780-423-5727, Fax: 780-429-3509


ISBN 1-896956-10-6

Acknowledgements